AskDefine | Define cerebroside

User Contributed Dictionary

English

Noun

  1. Any of several glycosphingolipids found in the membranes of muscle and nervous tissue

See also

Extensive Definition

Cerebrosides are glycosphingolipids which are important components in animal muscle and nerve cell membranes. Myelin is the most well known cerebroside.
They consist of a ceramide with a single sugar residue at the 1-hydroxyl moiety. The sugar residue can be either glucose or galactose; the two major types are therefore called glucocerebrosides and galactocerebrosides. Galactocerebrosides are typically found in neural tissue, while glucocerebrosides are found in other tissues.

Role in disease

A defect in the degradation of glucocerebrosides is Gaucher's disease. The corresponding defect for galactocerebrosides is Krabbe disease.
cerebroside in German: Cerebroside
cerebroside in Spanish: Cerebrósido
cerebroside in Italian: Cerebrosidi
cerebroside in Hebrew: צרברוזיד
cerebroside in Japanese: セレブロシド
cerebroside in Russian: Цереброзиды
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